Small molecule transcription modulators of bromodomains

Modulateurs de la transcription de petite molécule de bromodomaines

Abstract

This disclosure relates generally to compounds and compositions comprising one or more indole analogs. These compounds are useful for treating diseases associated with NF-kB and p53 activity, such as cancer and inflammatory diseases.
L'invention concerne d'une manière générale des composés et des compositions comprenant un ou plusieurs analogues d'indole. Ces composés sont utiles pour traiter des maladies associées à l'activité de NF-kB et de p53, telles que le cancer et les maladies inflammatoires.

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Patent Citations (1)

    Publication numberPublication dateAssigneeTitle
    US-2010022580-A1January 28, 2010Hung David T, Andrew Asher Protter, Sarvajit Chakravarty, Rajendra Parasmal JainNew 2,3,4,5-tetrahydro-1h-pyrido[4,3-b]indole compounds and methods of use thereof

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